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Association between risk of obstructive sleep apnea and cognitive performance,frailty, and quality of life among older adults with atrial fibrillation

Writer's picture: S-MedS-Med

In this contemporary study of older adults with AF in whom risk for OSA was characterized systematically, we observed a high prevalence of participants with an intermediate risk for OSA (53%). We also found that participants with an intermediate or high risk for OSA had higher odds of being frail but did not observe an association with cognitive performance after adjustment for potential con-founders.Geriatric impairments, including frailty and impaired cognition, commonly occur in patients with AF and have been shown to be associated with poor anti coagulation poor anti coagulation  and treatment-related outcomes, including increased risk of stroke and all-cause mortality.  On the other hand, OSA is also highly prevalent among patients with AF and is associated with higher risks of major bleeding and hospitalizations, poorer treatment outcomes, and often contributes to the maintenance and recurrence of AF.

To the best of our knowledge, no prior study has examined the association between OSA and geriatric elements including frailty and AF-related quality of life among patients with AF. Examining the associations between STOP-BANG assessed at year 2 and our study outcomes will help us identify patients at high risk who would benefit from screening for OSA.



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